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Severe hyperglycaemia may induce glucotoxicity in selective neurons involved in cognitive processing, with hippocampal neurons having been identified as particularly vulnerable to hyperglycaemia, and with proposed mechanisms including mitochondrial dysfunction and inflammatory responses [35]

Understanding the relationship between nicotine addiction and nAChR subtypes is crucial for fully uncovering the neurobiological mechanism behind its addictive properties and lays the foundation for developing more targeted smoking cessation strategies

By scavenging ROS, glutathione helps maintain the integrity and functionality of Leydig cells, promoting optimal testosterone production

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